I own two 3D printers, an Elegoo Centauri Carbon and a Voron, and for a long time I needed three slicers to drive them. PrusaSlicer doesn’t ship settings for my Elegoo. OrcaSlicer does, but it crashes often and generally doesn’t like my PC. Every so often Cura got pulled in too.

The bigger problem was the settings themselves. Both PrusaSlicer and Orca have hundreds of options, and their UIs show you all of them. Most stay at their defaults, so when I want to change one specific thing I end up hunting through tabs, guessing where it lives, and often guessing wrong. Orca also supports a huge number of printers, but it’s somewhat focused on Bambu Lab’s.